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Highlights

The local density of H3K9me3 dictates the stability of HP1a condensates mediated genomic interactions

tPE, SnPE: Enhancing Prime Editing Efficiency and Flexibility with Tethered and Split pegRNAs

EpiGo-KRAB: Simultaneous epigenetic perturbation and genome imaging reveal distinct roles of H3K9me3 in chromatin architecture and transcription


Latest news

Jun. 08,2023, Congratulations to Yuxi Tan (谭宇希) and Lingyun Li (李凌云) to become Ph.D. students.

April. 26,2023, "The local density of H3K9me3 dictates the stability of HP1a condensates-mediated genomic interactions" was published in Journal of Genetics and Genomics. Congratulation to Feng Ying (冯颖) in our lab

Jan. 01,2023, Congratulations to Yingdi Zhao(赵英迪) join the lab.

Dec. 01,2022, Congratulations to Wenlong Sun(孙文龙) to graduate.

Jun. 20,2022, Congratulations to Siyuan Liu(刘思远) to become Ph.D. students.

April. 6,2022, We posted our manuscript "Enhancing Prime Editing Efficiency and Flexibility with Tethered and Split pegRNAs" on Protein & Cell.

Jan. 1, 2022, Welcome Yuxi Tan (谭宇希) and Lingyun Li (李凌云) join the lab.

May. 14,2021, Congratulations to Xiaohui He(何晓慧) and Linxiao Han(韩林晓) to become Ph.D. students.

March. 15, 2021, Welcome Dingzhe Pu (濮定哲)Qiqin Mo (莫淇钦) joined in the lab.

Jan. 1, 2021, Welcome Siyuan Liu (刘思远) joined in the lab.

Dec. 8, 2020, Our EpiGo system was published in Genome Biology. Congratulation to Feng Ying (冯颖) in our lab and Yao Wang (王瑶) in Wei Xie's lab at Tsinghua University.