Engineering miniature IscB Nickase for Robust Base Editing with Broad Targeting Range
Linxiao Han#, Yueer Hu#, Qiqin Mo#, Hao Yang, Quanjiang Ji, Feng Gu, Fang Bai, Yadong Sun, Hanhui Ma*
Nature Chemical Biology (Accepted), 2024
Robust miniature Cas-based transcriptional modulation by engineering Un1Cas12f1 and tethering Sso7d
Xiangnan Wang#, Lingyun LI#, Guo Li, Ying Feng, Zengming Du, Wei Jiang, Xia Wu, Jing Zheng, Xiao Xiao, Hui Zheng, Yadong Sun, Hanhui Ma*
Molecular Therapy, 2024
Engineering Miniature CRISPR-Cas Un1Cas12f1 for Efficient Base Editing
Yueer Hu#, Linxiao Han#, Qiqin Mo, Zengming Du, Wei Jiang, Xia Wu, Jing Zheng, Xiao Xiao, Yadong Sun, Hanhui Ma*
Molecular Therapy: Nucleic Acids, 2024
Tracking paired-wise genomic loci by the ParB–ParS and Noc-NBS systems in living cells
Xiaohui He#, Yuxi Tan#, Ying Feng, Yadong Sun, Hanhui Ma*
Nucleic Acid Research, 2024
Enhancing Prime Editing Efficiency and Flexibility with Tethered and Split pegRNAs
Ying Feng#, Siyuan Liu#, Qiqin Mo, Xiao Xiao, Pengpeng Liu, Hanhui Ma*
Protein & Cell, 2022
Simultaneous epigenetic perturbation and genome imaging reveal distinct roles of H3K9me3 in chromatin architecture and transcription
Feng Y.#, Wang Y.#, Wang X., He X., Yang C., Naseri A., Pederson T., Zheng J., Zhang S., Xiao X., Xie W.*, & Ma H.*
Genome Biology, 2020
Cell cycle– and genomic distance–dependent dynamics of a discrete chromosomal region
Ma H.#, Tu L. C.#, Chung Y. C.#, Naseri A., Grunwald D., Zhang S., Pederson T.*
Journal of Cell Biology, 2019
CRISPR-Sirius: RNA scaffolds for signal amplification in genome imaging
Ma H.#, Tu L. C., Naseri A., Chung Y. C., Grunwald D., Zhang S., Pederson T.*
Nature Methods, 2018
CRISPR-Cas9 nuclear dynamics and target recognition in living cells.
Ma H.#, Tu L. C.#, Naseri A., Huisman M., Zhang S., Grunwald D., Pederson T.*
Journal of Cell Biology, 2016
Multiplexed labeling of genomic loci with dCas9 and engineered sgRNAs using CRISPRainbow.
Ma H.#, Tu L. C., Naseri A., Huisman M., Zhang S., Grunwald D., Pederson T.*
Nature Biotechnology, 2016
Multicolor CRISPR labeling of chromosomal loci in human cells
Ma H.#, Naseri A., Reyes-Gutierrez P., Wolfe S. A., Zhang S., Pederson T.*
PNAS, 2015
Visualization of repetitive DNA sequences in human chromosomes with transcription activator-like effectors
Ma H.#*, Reyes-Gutierrez P, and Pederson T.#
PNAS, 2013
# = Equal contribution
* = Corresponding author